Serum concentrations of Nostrin, NGAL and KIM-1 were compared between patients with versus without any of the following pre-existing morbidities: arterial hypertension, coronary artery disease (CAD), diabetes mellitus, heart insufficiency, history of neoplasia, chronic kidney disease, pulmonary disease or obesity. This evidence concerns the gene NOSTRIN and obesity due to melanocortin 4 receptor deficiency.