For example, NET1 eRNA regulates the expression of neuroepithelial cell transforming 1 (NET1) oncogene to promote tumorigenesis in breast cancer (Zhang et al. 2019) and HPSE eRNA regulates the expression of heparinase (HPSE) to promote the invasion and metastasis of cancer (Jiao et al. 2018). The gene discussed is HPSE; the disease is breast carcinoma.