CCR3 and cancer: CCL14 was considered to be a good prognostic biomarker in multiple cancer types and triggers the activation of monocytes, macrophages, and THP-1 cells through its binding affinity with CCR1, CCR3, and CCR5. Multiple studies suggest that CCL14 contributes to the development and advancement of different medical conditions, such as allergic airway inflammation and certain types of cancer (Gu et al. 2020; Wong et al. 2016; Zhu et al. 2019).