Eighteen hoursafter VRE infection, the percentage of annexin V+ PI+ RAW264.7 macrophages was ∼45%, which was reduced to15% in the presence of BOS (Figure S7B).In the presence of QNZ, the percentage of annexin V+ PI+ in BOS-treated infected macrophages was increased to ∼35%.Furthermore, QNZ did not inhibit macrophage killing of VRE in theabsence of BOS, but inhibited BOS-stimulated macrophage killing ofbacteria (Figure S7C). The gene discussed is ANXA5; the disease is Buschke-Ollendorff syndrome.