CD8A and neoplasm: It was therefore notable that ADC‐159 treatment caused a 3.16‐fold increase in CD8‐positive T‐lymphocytes per square millimetre of CT‐26 tumour as assessed by quantitative IHC (p = .0058, Figure 7A,B) and confirmed by flow cytometry (1.92‐fold increase, p = .0011, Figure 7C).