TNFSF12 and amyotrophic lateral sclerosis: Another remarkable discovery is the correlation of Tumor Necrosis Factor Ligand Superfamily Member 12 levels with the sporadic ALS validation set across three different SNP threshold groups, with a potential association observed with the mixed ALS set at SNP (p < 5 × 10−6) (OR > 1, P IVW < 0.05) (Figure 9) (Supplementary Tables S2–S4).