Furthermore, the study finds significant correlations between ALS risk and changes in levels of various inflammatory proteins, such as Interleukin-17C, Oncostatin-M, Interleukin-5 levels, SIR2-like protein 2 levels, Neurturin levels, TNF-beta levels and Interleukin-10, under different p-value thresholds. This evidence concerns the gene SIRT2 and amyotrophic lateral sclerosis.