According to Table 1 which indicates the missense or nonsynonymous variants, 29 genes can be prioritized including ABCA1, ABCB1, ACE, AGT, ALDH2, APOB, APOC1, APOE, CES1, CYP2B6, CYP2C9, EDN1, F7, FABP1, FMO3, ITGB3, KDR, LEPR, NOS3, NPPA, NR3C2, NT5C2, P2RY12, PON1, PTGS1, SCARB1, SH2B3, SLCO1B1, and TLR4. These genes can be considered for WES analysis for CAD patients or detecting CAD risk in healthy individuals as prognostic data. Here, TLR4 is linked to coronary artery disorder.