CD8A and neoplasm: ssGSEA showed that patients with high CAFs risk scores were enriched in antigen-presenting cell co-stimulation, macrophages, mast cells, and T-helper (Th) cells, whereas patients with low CAFs risk scores were enriched in CD8+ T cells, cytological activity, immature dendritic cells (iDCs), inflammation promotion, major histocompatibility complex class I, plasmacytoid DCs, T follicular helper cells, Th1 cells, tumor-infiltrating lymphocytes (TILs), and type I interferon responses (Fig. 8E–F).