Genes most strongly elevated in ALS blood included ribosomal protein L9 (RPL9), ribosomal L24 domain containing 1 (RSL24D1), vanin 2 (VNN2), mitochondrial amidoxime reducing component 1 (MARC1) and kynureninase (KYNU). This evidence concerns the gene VNN2 and amyotrophic lateral sclerosis.