There are data which demonstrate that in patients with the first episode of schizophrenia, the level of IL-1β, IL-2, IL-8, IL-4, IFNα and TNFα increased, and the content of pro-inflammatory cytokines, IL-1β, IL-8 and TNFα remained increased even after eight weeks of antipsychotic therapy with risperidone or haloperidol [32]. Here, TNF is linked to schizophrenia.