AFF1 and acute myeloid leukemia: IGF2BP1 is linked to pediatric AML and ETV6/RUNX1 B-ALL, while IGF2BP3 is linked to AML, KMT2A::AFF1 ALL, and BCR::ABL1 ALL (Stoskus et al., 2011; Palanichamy et al., 2016; Elcheva et al., 2020; Zhang et al., 2022).