The expression pattern of the set of genes involved in apoptosis (Figure S2B) and TNFA signaling via NFKB (Figure S2C) was closer to the phenotype of the wild‐type sample set, and to validate this finding we increased the number of clinical samples for immunohistochemical experiments, and there was higher expression of p‐MEK1\2 in the ARID1A mutation glioblastoma samples (Figure S2D,E). This evidence concerns the gene TNF and glioblastoma.