To further elucidate the underlying mechanisms, we compared the alterations in cell cycle and DNA damage repair proteins associated with wild‐type ARID1A, ARID1A KD, and ARID1A‐P16 deletion models to those in control glioma lines, following treatment with 200 μM TMZ, using Western blotting. The gene discussed is ARID1A; the disease is glioma.