We found that the mRNA levels of FTO, WTAP, and YTHDF2 were decreased with the increasing the concentration of Erastin or RSL3 in CRC cells, while the mRNA levels of ALKBH5, METLL3, and METLL14 were not significantly affected by Erastin or RSL3 (Fig. S2a, b). This evidence concerns the gene ALKBH5 and colorectal carcinoma.