PCSK9 expression was positively correlated with immune score, stomal score, and ESTIMATE score in BLCA (P < 0.001), BRCA (P < 0.001), pheochromocytoma and paraganglioma (PCPG) (P < 0.001) and THCA(P < 0.001). This evidence concerns the gene PCSK9 and pheochromocytoma.