In this study, glycovariants of stemness-related biomarker candidates OCT4, MET, CIP2A and LIMA1 were screened from two HNSCC cell lines and, further, from a panel of 25 HNSCC patients using samples of tumor tissue, adjacent normal tissue, and serum samples (Supplemental Fig. 1). This evidence concerns the gene POU5F1 and head and neck squamous cell carcinoma.