CENPA and cervical squamous intraepithelial neoplasia: Previously, we examined the consequence of CENP-A mislocalization in HeLa, RPE1, and DLD1 human cell lines, and provided the first evidence that the mislocalization of overexpressed CENP-A contributes to CIN by weakening the integrity of the native kinetochore (Shrestha et al, 2017; Shrestha et al, 2021).