PRKN and hypertrophic cardiomyopathy: In non-neoplastic diseases, high YTHDC1 expression can result in the upregulation of mitochondrial autophagy-related genes (PINK and PRKN) and increased myocardial energy expenditure in cardiomyocytes with hypertrophic cardiomyopathy, hence may be a potential biomarker for hypertrophic cardiomyopathy59.