40, 41 This inconsistency may be caused by differences in the timing of single-point measurements or variability in patient cohorts with restricted sample size (174−5267). Based on serial measurements from a broader population with suspected BSI, we found more pronounced CRP, WBC, heart rate, respiratory rate, and temperature responses to some Gram-positive bacteria (particularly S. pneumoniae and beta-haemolytic Streptococci) after adjusting for infection sources. Here, CRP is linked to infection.