Although many studies have demonstrated the expression of SARS-CoV-2 binding receptors, angiotensin-converting enzyme 2 (ACE2) and a transmembrane serine protease, TMPRSS2, on ocular surfaces [19,20] and the presence of viral RNA in conjunctival swabs [21,22], tears [23,24], and aqueous humor [25], the possible ocular transmission, tropism, pathology, and long-term effect of COVID-19 on eye remains inconclusive. The gene discussed is ACE2; the disease is COVID-19.