Telomere dysregulation has been implicated in gliomas, which maintain telomere length to avoid senescence and apoptosis, which is induced by the replicative shortening of their chromosomes during cell division.16–18 While this is commonly achieved by re-activating telomerase, telomeres can also be maintained by ALT pathway which involves DNA repair and recombination. This evidence concerns the gene GPT and glioma.