In all cases of this group, at CML diagnosis, both CALR mutation and BCR::ABL1 rearrangement were detected (Bonzheim et al., 2015; Kandarpa et al., 2017; Boddu et al., 2018; De Roeck et al., 2018; Klairmont et al., 2018; Xia et al., 2019; Liu et al., 2020; Sobieralski et al., 2022). Here, BCR is linked to chronic myelogenous leukemia, BCR-ABL1 positive.