In our cohort of IDH-mutant diffuse glioma, EGFR Amp was found to co-occur with FGFR1, FGFR2, NTRK3 and RB1 alterations, which was not completely consistent in astrocytoma and oligodendroglioma. The gene discussed is NTRK3; the disease is astrocytoma (excluding glioblastoma).