TP53 and astrocytoma (excluding glioblastoma): In previous studies, oligodendroglioma was found associated with CIC and FUBP1 due to the close chromosomal location of these genes and 1p/19q co-deletion (Sahm et al., 2012; Yip et al., 2012), while astrocytoma mostly presented TP53 and ATRX mutations (Cancer Genome Atlas Research Network et al., 2015).