In this regard, acute DSS colitis in conventional C57BL/6 mice decreased the expression of Ffar2, Ffar3, and Hcar2 (Lin et al., 2023; Nan et al., 2023), although this result was not confirmed by others (Kotlo et al., 2020; Han et al., 2021). The gene discussed is FFAR3; the disease is colitis.