Importantly, we also found shared genes between BC genes and hub genes, namely, App in BAT, Vegfa, App in WAT, Lep, Decr1, Cdh1, Cyp2e1, Acadl, Clu, Fgf21, Cfd, Plin5 in muscle, Ugt2b1 in liver, respectively. This evidence concerns the gene LEP and breast cancer.