Similarly, 14 days after UUO, the kidneys of MΦ atg5−/− mice revealed less renal fibrosis, as indicated using quantitative SR and Masson staining (Fig. 4, A–C), and reduced staining for fibrotic components (FN1, vimentin, and α-SMA) compared to WT littermate mice (Fig. 4, D–G). This evidence concerns the gene FN1 and renal fibrosis.