In the combined TCGA-GBM and LGG datasets, 387 DEGs were identified between high and low SIRPB1 expression samples, based on cut-off criteria of adjust P < 0.01 and |log2FC|> 1.5, including 352 up-regulated and 35 down-regulated genes (Additional file 1: Table S3). The gene discussed is SIRPB1; the disease is glioblastoma.