HMGB3 and melanoma: It is interesting to note that the overexpression of ten genes (AIMP2, AURKA, AURKB, CDC45, CDCA3, CKS1B, HMGB3, KPNA2, MCM5, and NCAPD2) and the low expression of three genes (NUPR1, and SLC1A3) were associated with poor prognosis in melanoma.