Here, several genes known to be up-regulated under S-deficiency in A. thaliana [10, 12, 13], were present, including SDI2, which together with SDI1 are involved in partitioning sulfur among metabolite pools during S- deficiency, controlling the glucosinolate biosynthesis in Arabidopsis under low S conditions [38, 39]. The gene discussed is CDKN1A; the disease is hyperinsulinemic hypoglycemia, familial, 4.