Furthermore, we identified 13 target genes (STK35, GRID1, ZNF268, PARP11, RAB5B, PDE7A, RNF40, KCND1, UBN2, TTPAL, CACNG8, ORAI2, and XIAP) that may be vital in AD and PSCI development. The gene discussed is GRID1; the disease is Alzheimer disease.