Furthermore, we identified 13 target genes (STK35, GRID1, ZNF268, PARP11, RAB5B, PDE7A, RNF40, KCND1, UBN2, TTPAL, CACNG8, ORAI2, and XIAP) that may be vital in AD and PSCI development. This evidence concerns the gene UBN2 and Alzheimer disease.