Furthermore, we identified 13 target genes (STK35, GRID1, ZNF268, PARP11, RAB5B, PDE7A, RNF40, KCND1, UBN2, TTPAL, CACNG8, ORAI2, and XIAP) that may be vital in AD and PSCI development. Here, RAB5B is linked to Alzheimer disease.