Six of the proteins were consistently differentially regulated with the protein either being up regulated by infection with both DENVs (four proteins namely 26S proteasome non-ATPase regulatory subunit 13, Complement component 1 Q subcomponent-binding protein, T-complex protein 1 subunit beta, Eukaryotic translation initiation factor 3 subunit I) or down regulated by infection with both DENVs (two proteins namely Prohibitin and Ubiquitin carboxyl-terminal hydrolase isozyme L1). This evidence concerns the gene PHB1 and infection.