Moreover, DLB has been associated with an increase in the circulating levels of several proinflammatory cytokines including IL2, IL17A and C-C motif chemokine ligand 20 (CCL20) along with decreased IL8 concentrations153, pointing to an involvement of both innate and adaptive immune mechanisms in the pathogenesis of the disease. The gene discussed is IL17A; the disease is Lewy body dementia.