Considering that iNOS is one of the hallmarks of tumoricidal pro‐inflammatory macrophages, and that the nitric oxide (NO) produced by iNOS exerts anti‐tumor activity,[61] further studies are warranted to investigate the mechanism by which the changed release pattern of DAMPs from the MCP‐deficient tumor cells stimulates the transcription of iNOS. The gene discussed is NOS2; the disease is neoplasm.