Cancer chemoresistance has been associated with overexpression of anti-apoptotic BCL2 family members (Ding et al. 2020), whereas high amounts of pro-apoptotic proteins, such as caspase 3, Bax, and p53, accelerate apoptosis and make tumor cells more responsive to anticancer therapy (Kim et al. 2007). The gene discussed is BAX; the disease is neoplasm.