In agreement with that described by Rodriguez et al. [58] via immunohistochemical analysis, Yoon BS et al. also reported that high expression of HLA-G mRNA was correlated with early cervical cancer [59], and at the same time, other authors have highlighted that HLA-G levels are inversely proportional to the percentage of lymphocytes infiltrating the tumor [60]. This evidence concerns the gene HLA-G and neoplasm.