Significantly higher concentrations of IgG APSA in NTG with progressive SNHL compared to normal hearing and controls were also found by Bachor et al., who additionally found the concentrations of IgM APSA were significantly elevated in all subgroups of NTG patients, as well as in in NTG patients with normoacusis, compared to controls [91]. This evidence concerns the gene CD40LG and sensorineural hearing loss disorder.