The research revealed nine genes that may be connected with inguinal hernia, such as Prochorionic Villous Corticotropin (POMC), CD40 Ligand (CD40LG), Transferrin Receptor (TFRC), Von Willebrand Factor (VWF), Lysosomal Oxidase (LOX), Insulin-like Growth Factor 2 (IGF2), DNA repair-related BRCA1 (BRCA1), Tumor Necrosis Factor (TNF), and Hepatocyte Growth Factor (HGF) in the plasma. The gene discussed is IGF2; the disease is Inguinal hernia.