Qiu et al. (2023) research has found that enhanced autophagy is accompanied by limited proliferation of oral squamous cell carcinoma. Gao et al. (2020) demonstrated that disruptors of autophagy, specifically via the PI3K/AKT/mTOR pathway, contribute to tumor progression and chemoresistance in laryngeal squamous cell carcinoma. This evidence concerns the gene AKT1 and oral cavity squamous cell carcinoma.