EDN1 and apparent mineralocorticoid excess: As illustrated in Figs. 3C–3F, the serum levels of ET-1 and TXB2 were higher (P < 0.01), while the levels of 6-K-PGF1α and NO were lower in the APE group at 2 h, 6 h, 1 d, and 2 d (P < 0.01) compared to the control group.