FASN and adenoma: Interestingly, heterozygous deletion of FASN in intestinal epithelial cells leads to a significant decrease in the levels of several diglyceride species (C16:1:20:0-DAG; Di-C14-DAG; C14:0:18:0-DAG; C16:1:18:0-DAG; C18:0:18:1-DAG) in mouse adenoma tissues but does not affect the total levels of free fatty acid and sphingolipid species (34).