As suggested by the forest plot for univariable COX regression, high CD44 expression was related to dismal OS in thymic epithelial neoplasms(THYM), STAD, PAAD, and MESO brain lower grade glioma (LGG) [hazard ratio (HR)>1, P<0.05), whereas CD44 served as the good prognostic factor for OS in THCA (HR<1, P<0.05) (Figure 2B). This evidence concerns the gene CD44 and gastric adenocarcinoma.