CD44 and pancreatic adenocarcinoma: As shown by the Kaplan-Meier survival analysis, CD44 up-regulation was indicative of shortened OS and DSS of GBM, BLCA, STAD, liver hepatocellular carcinoma (LIHC), PAAD, and KIRC, while it was associated with prolonged OS or DSS in UCEC, THCA and BRCA (Figure 2A; Supplementary Figure S2A).