AKT1 and asthma: The protein expressions of phosphorylated PI3K and AKT in lung tissues of BYD-treated mice were significantly diminished compared to those in the model group, implying that BYD may modulate airway inflammation in asthma mice by suppressing the phosphorylation of PI3K and AKT and inhibiting the activation of the PI3K/AKT signaling pathway (Figures 7B, C).