Luteolin exhibited inhibitory effects on airway inflammation in mice with allergic or neutrophilic asthma, and it modulated the PI3K/AKT/mammalian target of rapamycin (mTOR) signaling pathway to inhibit autophagy in allergic asthma (Wang et al., 2021; Qiao et al., 2023). This evidence concerns the gene AKT1 and allergic asthma.