TNF and asthma: Visual images of KEGG pathway enrichment analysis (Figures 2E, F) indicated the BYD-asthma targets were mainly concentrated in the PI3K/AKT signaling, tumor necrosis factor (TNF) signaling, Th17 cell differentiation, hypoxia inducible factor-1 (HIF-1) signaling, and IL-17 signaling pathways, which are closely associated to the immune inflammation in asthma.