Conversely, in patients with relapsed acute myeloid leukemia, TNFRSF4 expression is significantly increased in CD8+ T cells and regulatory T cells (Tregs) when compared to healthy donors (192).TNFRSF4 has been identified as a novel molecule in endometrial cancer (EC), and its increased expression is associated with favorable clinical outcomes. Here, TNFRSF4 is linked to acute myeloid leukemia.