HLA-DRB1 and multiple sclerosis: Supplementary Table 9 shows the number of SVA_27/DRB1*15 or DRB1*16/DQA1 haplotypes in the PPMI cohort, including DRB1*15:01/DQA1*01:02, which is associated with protection from T1D (54) and susceptibility for multiple sclerosis (55). Of the 194 DRB1*15:01/SVA_27 haplotypes in PPMI, 178 (91.8%) are linked to DQA1*01:02/DQB1*06:02. Of the 50 DRB1*16/SVA_27 haplotypes, 39 (78%) are linked to DQA1*01:02:02/DQB1*05:02:01.