These factors included age (p = 0.040), Mini-Mental State Examination score (p < 0.001), State-anxiety inventory score (p = 0.014), Trait-anxiety inventory score (p = 0.003), anesthesia time (p = 0.006), hospitalization time (p < 0.001), and IL-6 concentration at T3 (p = 0.003). The gene discussed is IL6; the disease is Anxiety.