The MYC/AURKA signalling axis is exacerbated by the overexpression of the inhibitor of differentiation 1 (ID1), which competes with APC/C‐Cdh1 for binding, thereby impairing the ubiquitin‐mediated degradation of AURKA and facilitates HCC progression (Figure 4).99 The gene discussed is ID1; the disease is hepatocellular carcinoma.