For example, up-regulation of FXYD5 has been shown to correlate with tumor size [53] and poor survival [54] in NSCLC and to be implicated in many cancer types as FXYD5 enhances NFκ-B transcriptional activity, promotes angiogenesis and increases tumor cell’s migration and invasion abilities [55]. The gene discussed is NFKB1; the disease is neoplasm.