We found that there was a predominance of high expression (≥ 2 scoring) both of the tumor cells (n = 67) and tumor vasculature (n = 49) (Fig. 1b, c) compared with known high BTK expressing lymph tissue and low expressing BTK seen in liver, colon, lung and soft tissue (Additional file 1: Fig. 1a). This evidence concerns the gene BTK and neoplasm.