These findings have been substantiated by the same researchers after correcting for cognitive decline and AD pathology, which pointed to increased STX1A, SNAP25, SYT12 and decreased SYN2, vesicle associated membrane protein 5 (VAMP5), vesicle amine transport 1 (VAT1) and SLC6A12 in resilience [101]. This evidence concerns the gene VAMP5 and Alzheimer disease.