For example, SF3B1 regulates erythroid-cell proliferation and maturation [18, 19], and balances the differentiation of neutrophils and monocytes [20] through the transcription factor ELK1, which is associated with AML [21] and is regulated by the antioxidant α-lipoic acid (ALA). Here, ELK1 is linked to acute myeloid leukemia.