CD14 and neoplasm: At the same time, ALA increased the production of CD66b– CD14+ monocytes, while decreased the production of CD66b+CD14– neutrophils [20] and CD66b+CD14+ proinflammatory monocytes [33] or antigen-presenting cells (APCs)-like tumor associate neutrophil like cells [34] derived from CD34+ HSPCs (Fig. 1B, C).