Our findings revealed a positive correlation between TUBA1B expression and the expression of m6A methylation-related genes in numerous malignancies, with ACC, BLCA, KICH, KIRP, LIHC, SKCM, and UCEC showing particularly strong associations, thereby suggesting that TUBA1B may exhibit elevated levels of m6A methylation in these cancer types. The gene discussed is TUBA1B; the disease is adrenal cortex carcinoma.