Overall, our findings consistently demonstrated that higher TUBA1B expression correlated with poorer prognosis in these cancers, affecting various survival metrics such as overall survival (OS), progression-free survival (PFS), disease-specific survival (DSS), distant metastasis-free survival (DMFS), and disease-free survival (DFS) (Cox p < 0.05; Fig. 3). This evidence concerns the gene TUBA1B and cancer.