Using the PrognoScan database, we analyzed cancer patients with varying levels of TUBA1B expression to assess its impact on their prognosis in 15 datasets from diverse cancer types, including (GSE5287, GSE13507, GSE19615, GSE9195, GSE1456, GSE7378, GSE3494, GSE4922, GSE4412, GSE13213, GSE31210, GSE19234, GSE17710, GSE8894, and GSE9891) from BLCA, BRCA, glioma, LUAD, SKCM, LUSC, non-small cell lung carcinoma (NSCLC), and OV. Here, TUBA1B is linked to central nervous system cancer.