Three main hypothetical mechanisms through which COVID-19 vaccines could trigger autoimmunity are: molecular mimicry (immune cross-reactivity due to similarities between certain vaccine components and specific human proteins), the production of autoantibodies (e.g., anti-platelet factor 4 antibodies), and the specific vaccine adjuvants (by triggering innate inflammatory responses)9,30. Here, PF4 is linked to Autoimmunity.